Simplified method to quantify valve back‐leak uncovers severe mesenteric lymphatic valve dysfunction in mice deficient in connexins 43 and 37
نویسندگان
چکیده
منابع مشابه
Severe Persistant Cyanosis in a Newborn Due to Prominent Eustachian Valve
ABSTRACTThe valves of right horn of systemic venous sinus are prominent structures within the right atrium during early embryonic period. Involution of these structures may not be complete, resulting in a spectrum of anatomical presentations such as cyanosis. A full-term male neonate referred to our hospital for precise evaluation of severe cyanosis on the first day of life. Echocardiographic e...
متن کاملTranscatheter Valve-in-Valve and Valve-in-Ring for Treating Aortic and Mitral Surgical Prosthetic Dysfunction.
Bioprosthetic valve use has increased significantly. Considering their limited durability, there will remain an ongoing clinical need for repairing or replacing these prostheses in the future. The current standard of care for treating bioprosthetic valve degeneration involves redo open-heart surgery. However, repeat cardiac surgery may be associated with significant morbidity and mortality. Wit...
متن کاملInterleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice.
Calcific aortic valve disease is a chronic inflammatory process, and aortic valve interstitial cells (AVICs) from diseased aortic valves express greater levels of osteogenic factors in response to proinflammatory stimulation. Here, we report that lower cellular levels of IL-37 in AVICs of diseased human aortic valves likely account for augmented expression of bone morphogenetic protein-2 (BMP-2...
متن کاملLymphatic metastasis in the mitral valve.
Involvement of the heart by metastatic neoplasm is not uncommon. Postmortem studies of patients with malignant disease show that cardiac involvement occurs in up to 21 per cent of cases (Bisel, Wr6blewski, and LaDue, 1953). The pericardium, epicardium, and myocardium are the areas of the heart most commonly involved by secondary tumour; spread to the endocardium and heart valves is rare (Coller...
متن کاملMitral valve aneurysm due to severe aortic valve regurgitation.
A33-year-old man presented to the hospital with shortness of breath and chest pain. He was subsequently diagnosed with Streptococcus mitis endocarditis involving the aortic valve. The initial echocardiogram revealed moderate aortic valve regurgitation and a normal mitral valve without regurgitation. The patient was treated with afterload reduction and antibiotics. Blood cultures were negative w...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2020
ISSN: 0022-3751,1469-7793
DOI: 10.1113/jp279472